How to Get Rid of Pee Smell on a Mattress

Learn proven, step-by-step methods to remove urine odors from a mattress. This guide covers cleaning, odor neutralizers, drying techniques, and prevention tips from Mattress Buyer Guide to keep your bed fresh.

Mattress Buyer Guide
Mattress Buyer Guide Team
·5 min read
Odor-Free Sleep Guide - Mattress Buyer Guide
Photo by jarmolukvia Pixabay
Quick AnswerSteps

Goal: completely remove urine odor from a mattress and prevent resale odors. Start by blotting to remove moisture, then treat with an enzyme-based cleaner designed for urine and follow with a deodorizing solution. Ensure thorough drying with fans or a dehumidifier; repeat as needed. According to Mattress Buyer Guide, patience and thorough drying are key to lasting odor removal.

Understanding why pee smells linger

Urine odors cling to mattresses for a few reasons. Urine contains ammonia and uric acid, which can bind to fibers and padding. When moisture is trapped inside the mattress, bacteria continue to metabolize the liquids, releasing odor compounds over time. This is why even a quick spill can seem to fade and then reappear after a few hours. If you’re looking to get rid of pee smell on mattress, the goal is to remove moisture, neutralize odor-causing particles, and dry the layers thoroughly. According to Mattress Buyer Guide, patience and a thorough drying process are essential to lasting odor removal.

Cleaning agents: enzyme cleaners vs. alternatives

The most effective cleaners for urine odors are enzyme-based products. Enzymes break down uric acid and proteins that cause odors, making it easier for subsequent deodorizing agents to work. Generic cleaners may mask smells temporarily but often leave residual odor. As Mattress Buyer Guide Analysis, 2026 notes, enzyme cleaners paired with proper drying deliver the strongest long-term results. If enzyme cleaners aren’t available, a vinegar-water solution can help, but it’s not as reliable for deep odors.

Immediate cleanup steps (first 24 hours)

Act quickly after an accident. Blot with clean towels to remove excess moisture—press gently without rubbing to avoid forcing liquids deeper into the foam. Collect and dispose of any solids, then apply the enzyme cleaner according to label instructions. Allow the product to sit for the recommended dwell time, then blot again. This rapid response minimizes the risk of set-in odors.

Deep cleaning for persistent odors

If odors linger, perform a deeper treatment. After the dwell time on the enzyme cleaner, lightly mist the area with clean water to rinse, then blot thoroughly. Sprinkle baking soda over the treated area and let it sit for 6–12 hours; this helps absorb remaining moisture and odors. Vacuum the baking soda residue completely and inspect for any remaining damp spots. Repeat enzyme treatment if necessary.

Drying and odor sealing to prevent odor return

Drying is the critical step. Use a fan or a dehumidifier to circulate air and accelerate evaporation. If possible, place the mattress in a well-ventilated area away from direct sunlight to avoid material damage. Once dry, consider a breathable mattress protector or cover to seal in cleanliness and deter future spills. Mattress Buyer Guide suggests a protective cover for ongoing odor prevention.

Prevention: protective covers and mattress protectors

Preventive measures save time and money. Use a washable, moisture-resistant mattress protector and avoid sleeping on damp bedding after an accident. Regularly vacuum the mattress surface to remove dust and moisture pockets. Keep pets off the bed in the immediate aftermath of spills to avoid cross-contamination. These steps reduce the chance of repeat odors.

When to replace vs sanitize

Some odors may be beyond salvage, especially if the spill was large or penetrated into the core layers. If repeated cleanings fail to remove smells after several attempts, or if you notice discoloration, peeling, or mildew, replacement may be the best option. A new mattress with a protective cover can be a better investment in sleep quality and hygiene.

Common mistakes to avoid

Avoid rubbing vigorously, which can push urine deeper. Don’t mix cleaners unless the label explicitly allows it. Never apply heat to a wet mattress, which can set stains and odors. Skip using bleach on most mattresses, as it can damage fabrics and foam. Finally, don’t rush drying—prematurely closing the case traps moisture and odors inside.

Assessing odor after cleaning

After the mattress has dried, do a thorough sniff test and visually inspect for dampness. If odors persist, repeat the enzyme cleaning process in a larger area or consider professional cleaning services. Maintain vigilance with a protective cover to prevent recurrence, and monitor any changes in odor over the following days.

What to do if the mattress is heavily soiled

Heavily soiled mattresses require patience and multiple passes. Start by removing the top cover if it’s removable and washing per manufacturer instructions. Use an enzyme cleaner to address deeper odors, then extract as much moisture as possible with a wet-dry vacuum or portable extractor. Drying may take longer in humid rooms; keep air moving and avoid covering the mattress until fully dry. If odor or staining persists beyond 72 hours of drying, it may be time to replace or consult a professional service.

Tools & Materials

  • Enzyme-based urine odor remover(Choose a product with proven enzyme action; follow label directions.)
  • Clean water(For rinsing and dampening.)
  • White vinegar (optional)(Natural deodorizer; use sparingly.)
  • Baking soda(Absorbs odors; not essential.)
  • Spray bottle(For even application of cleaners.)
  • White microfiber cloths(For blotting and wiping.)
  • Vacuum cleaner with upholstery attachment(To remove dry residues.)
  • Box fan or dehumidifier(Speeds up drying.)
  • Mattress protector(Use after cleaning to prevent future odors.)
  • Gloves (optional)(Protect hands during cleaning.)

Steps

Estimated time: 6-10 hours

  1. 1

    Blot to remove moisture

    Place clean towels on the stain and press firmly to absorb as much liquid as possible without rubbing. Lift and repeat with fresh towels until no moisture transfers. This step reduces the amount of liquid that can seep deeper.

    Tip: Press, don’t rub; rubbing can push urine further into the foam.
  2. 2

    Apply enzyme cleaner

    Spray or apply the enzyme cleaner evenly over the affected area until damp but not soaking. Leave it to dwell per the product label to break down uric acid and proteins.

    Tip: Work from the center outward to avoid spreading the stain.
  3. 3

    Rinse or blot after dwell time

    Gently blot with clean water or a damp cloth to remove excess cleaner, then blot dry again. Do not saturate the mattress with water; excess moisture can worsen odors.

    Tip: Use a fresh towel for each blot to prevent reintroducing contaminants.
  4. 4

    Absorb with baking soda

    Lightly dust baking soda over the treated area to absorb remaining moisture and odors. Let it sit for 6–12 hours for best absorption, then vacuum completely.

    Tip: Avoid letting powder cake up in seams; apply a thin, even layer.
  5. 5

    Dry thoroughly with air flow

    Run a box fan or dehumidifier in the room and keep air moving over the mattress. If possible, place the mattress in a dry, shaded area to expedite evaporation.

    Tip: More airflow equals faster drying and less chance of odor reappearing.
  6. 6

    Protect against future incidents

    Once dry, cover the mattress with a breathable protector and consider changing bedding promptly after accidents to reduce residual moisture.

    Tip: Choose a protector that is washable and waterproof for best results.
  7. 7

    Evaluate and repeat if needed

    If odors persist after the area has thoroughly dried, repeat the enzyme cleaning process on a larger area or target additional surrounding fibers. Some deep odors require multiple passes.

    Tip: Don’t skip the drying phase between repeats to prevent mold.
Pro Tip: Always test cleaners on a hidden spot first to avoid color damage.
Warning: Never mix ammonia-based cleaners with bleach or hydrogen peroxide; this can release dangerous fumes.
Note: Use clean, dry towels for blotting to minimize cross-contamination.

FAQ

Can a mattress be completely deodorized after urine exposure?

Most odors can be significantly reduced with enzyme cleaners and thorough drying. Deep-set odors may linger if the spill penetrated the core layers.

Most odors can be significantly reduced with enzyme cleaners and thorough drying; deep odors may persist if the spill was severe.

Is baking soda effective for pee smell on mattresses?

Baking soda helps absorb remaining moisture and odor after cleaning, but it should be used in combination with enzyme cleaners and proper drying. It’s not a standalone solution.

Baking soda helps absorb odors after cleaning, but it's best used with enzyme cleaners and adequate drying.

Bleach on urine stains?

Bleach can damage mattress materials and should generally be avoided. Stick to enzyme cleaners or mild options suitable for your mattress type.

Bleach can damage mattress materials, so avoid it and use enzyme cleaners instead.

Drying time after cleaning?

Drying times vary with humidity and mattress type, but plan for several hours of airflow, followed by 24 hours before using the bed again. Do not compress the mattress while damp.

Drying can take several hours, with up to a full day before resale; keep it unflexed and well-ventilated.

Move mattress during cleanup?

If you can safely move it, do so to expose damp areas and improve airflow. Avoid dragging to prevent damage.

Move it if you can safely do so; better airflow helps drying and odor removal.

What if odor returns?

If odors return after cleaning, repeat the enzyme treatment on a larger area and re-check for complete drying. Persistent odors may require professional cleaning or replacement.

If it returns, re-clean with enzyme cleaner and ensure thorough drying; consider professional help if needed.

Watch Video

Highlights

  • Act quickly to blot and start cleaning.
  • Enzyme cleaners deliver the strongest odor removal.
  • Dry thoroughly to prevent odor return.
  • Protect with a mattress cover to avoid future stains.
  • If odors persist, consider replacement or professional help.
Process diagram for removing urine odor from a mattress
4-step process to remove urine odors from mattresses

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